Vitamin E is one of the body’s most important antioxidant nutrients. Antioxidants protect healthy cells from
oxidative and free radical damage. Free radicals are unstable chemicals formed in the body during
metabolism and from exposure to environmental sources, such as pollution and cigarette smoke. Free
radicals are necessary for energy metabolism and immune function, however, maintaining an appropriate
balance is an important factor for cellular health, especially cell membrane lipids and proteins.
Vitamin E is an especially valuable antioxidant in the cell membranes, where it prevents oxidation of
unsaturated fatty acids by trapping free radicals. his helps stabilize and protect cell membranes, especially red
blood cells and tissues sensitive to oxidation, such as the lungs, eyes, and arteries.† Vitamin E also protects
the liver and other tissues through its antioxidant properties.
Selenium is a nutritionally essential trace element for humans and animals. The National Research Council’s
Recommended Dietary Allowance for selenium in adults ranges from 55 to 75 mcg per day depending on age
and gender. Selenium is a cofactor to about 10 selenoproteins in the body; the most important of these
appears to be glutathione peroxidase (GPX). GPX uses glutathione to reduce hydrogen peroxide and thus
protect cells and plasma against free radical injury.† GPX activity depends on an adequate supply of dietary
selenium. Recently, selenium as selenocysteine has been identified in the active center of type 1 and 3
iodothyronine deiodinases, two important enzymes regulating the active thyroid hormone, triiodothyronine